浙江大學醫(yī)學院導師：陳懷增 正文

　　姓名：陳懷增
　　性別：男
　　所在學院：醫(yī)學院
　　職稱：副研究員

　　研究方向：
　　婦科腫瘤

　　發(fā)表論文：　
　　1．Loss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous carcinomaLoss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous c　European Journal of Gynacological Oncology28<6>, Chen H,Ye F, Zhang J, Lu W,Cheng Q, Xie X
　　 2．No association of the POLI Thr706Ala polymorphism with the risk of cervical carcinomaNo association of the POLI Thr706Ala polymorphism with the risk of cervical carcinoma　European Journal of Gynacological Oncology<>, Zhang J, Ye F, Cheng Q,Shen J, Chen H

　　1．Tapasin和HLAⅠ類分子在人卵巢癌中的表達及相關(guān)性Tapasin和HLAⅠ類分子在人卵巢癌中的表達及相關(guān)性　14<4>,
　　2．人乳頭瘤病毒的分子生物學特性研究現(xiàn)狀人乳頭瘤病毒的分子生物學特性研究現(xiàn)狀　28<4>,
　　3．卵巢癌細胞死亡形式對巨噬細胞細胞毒作用的影響　中華婦產(chǎn)科雜志39<4>, 樓海亞，葉大風，陳懷增，呂衛(wèi)國，付云峰，謝幸
　　4．Interleukin-7 and suppression of local peritoneal immunity in ovarian carcinomaInterleukin-7 and suppression of local peritoneal immunity in ovarian carcinoma　International Journal of Gynecology and Obstetrics85<>, X． Xie, D． Ye, H． Chen, W． Lu, B． Cheng, H． Zhong
　　5．卵巢上皮性癌生長抑素受體2表達的研究　中華婦產(chǎn)科雜志37<5>, 陳懷增，謝幸，葉大風，呂衛(wèi)國
　　6．卵巢粘液性腫瘤hMLHl啟動子甲基化及微衛(wèi)星不穩(wěn)定性　中國醫(yī)學科學院學報25<4>, 陳懷增，葉大風，謝幸，胡旻，呂衛(wèi)國
　　7．體外γ干擾素對臍靜脈內(nèi)皮細胞ECV-304的作用　中華醫(yī)學雜志83<11>, 陳懷增，林仿芳，謝幸，葉大風，呂衛(wèi)國
　　8．γ-干擾素對卵巢癌細胞株血管內(nèi)皮生長因子表達的影響　中華婦產(chǎn)科雜志38<3>, 林仿芳，陳懷增，謝幸，葉大風
　　9．白細胞介素7基因轉(zhuǎn)染卵巢癌細胞的體外研究　中華婦產(chǎn)科雜志38<4>, 程蓓，陳懷增，葉大風，呂衛(wèi)國，謝幸
　　10．免疫重建荷卵巢癌SKOV3 SCID鼠腹腔移植中IL-7的免疫學作用　中華微生物學和免疫學雜志23<12>, 葉大風，陳懷增，謝幸，呂衛(wèi)國，朱華，潘子民
　　11．卵巢癌患者CD4＋CD25＋調(diào)節(jié)性T細胞比例增高及可能機制　中華微生物學和免疫學雜志 2004；24（7）：574-575。24<7>, 李曉，陳懷增，謝幸，葉大風，呂衛(wèi)國，丁志明
　　12．VEGF、VEGFRs Expressions and activated STATs in ovarian epithelial carcinoma VEGF、VEGFRs Expressions and activated STATs in ovarian epithelial carcinoma 　Gynecol Oncol94<>, Huaizeng Chen, Dafeng Ye, Xing Xie*, Bingya Chen, Weiguo Lu
　　13．Mismatch Repair Gene Promoter Methylation and Expression in Hydatidiform molesMismatch Repair Gene Promoter Methylation and Expression in Hydatidiform moles　Arch Gynecol Obstet<272>, Huaizeng Chen, Dafeng Ye, Xing Xie*, Weiguo Lu, Changkun Zhu, Xiaodong Chen
　　14．PTEN Promoter Methylation and Protein Expression in Normal Early Placentas and Hydatidiform MolesPTEN Promoter Methylation and Protein Expression in Normal Early Placentas and Hydatidiform Moles　J soc gynecol invest12<>, Huaizeng Chen , Dafeng Ye , Xing Xie *, Weiguo Lu, Changkun Zhu and Xiaodong Chen
　　15．用ELISA測定卵巢癌患者血清、腹腔液VEGF水平及其臨床意義　浙江醫(yī)學23<11>, 傅云峰，謝幸，葉大風，陳懷增，呂衛(wèi)國
　　16．卵巢上皮性癌患者白細胞介素-7測定的臨床意義　實用腫瘤雜志16<5>, 鐘惠珍，謝幸，謝建華，葉大風，呂衛(wèi)國，陳懷增
　　17．The Value of Curettage in Diagnosis of Endometrial HyperplasiaThe Value of Curettage in Diagnosis of Endometrial Hyperplasia　Gynecologic Oncology84<>, Xing Xie, Wei-Guo Lu, Da-Feng Ye, Huai-Zeng Chen, Yun-Feng Fu
　　18．Ovarian carcinoma cells inhibit T cell proliferation:suppression of IL-2 receptor and g expression and their JAK-STAT signaling pathwayOvarian carcinoma cells inhibit T cell proliferation:suppression of IL-2 receptor and g expression a　Life Sciences74<>, Hui Wang, Xing Xie*, Wei-guo Lu, Da-feng Ye, Huai-zeng Chen, Xiao Li, Qi Cheng
　　19．子宮內(nèi)膜增殖癥診斷性刮宮價值的評價　中華醫(yī)學雜志81<13>, 呂衛(wèi)國，謝幸，葉大風，陳懷增，傅云峰，陳曉端
　　20．卵巢上皮性癌患者28例血清和腹腔液VEGF測定及其診斷價值初探　中國實用婦科與產(chǎn)科雜志18<10>, 傅云峰，謝幸，葉大風，陳懷增，呂衛(wèi)國
　　21．轉(zhuǎn)化生長因子β1、白細胞介素2、7與卵巢上皮性癌患者腹腔局部免疫功能的關(guān)系　現(xiàn)代婦產(chǎn)科進展11<5>, 呂衛(wèi)國，葉大風，謝幸，陳懷增，傅云峰
　　22．卵巢上皮癌IL-7mRNA表達的研究　現(xiàn)代婦產(chǎn)科進展11<2>, 程蓓，謝幸，葉大風，陳懷增，呂衛(wèi)國
　　23．人參皂甙Rg3對荷卵巢癌的嚴重聯(lián)合免疫缺陷鼠的抗腫瘤血管生成作用的研究　中華婦產(chǎn)科雜志37<4>, 潘子民，葉大風，謝幸，陳懷增，呂衛(wèi)國
　　24．卵巢上皮性癌血管內(nèi)皮生長因子mRNA異構(gòu)體表達　浙江大學學報（醫(yī)學版）31<1>, 傅云峰，謝幸，葉大風，陳懷增，呂衛(wèi)國
　　25．甲氨蝶呤單藥治療低危妊娠滋養(yǎng)細胞腫瘤的療效　中國醫(yī)學科學院學報25<4>, 呂衛(wèi)國，丁志明，謝幸，葉大風，陳懷增，馮素文
　　26．錯配修復基因啟動子甲基化和蛋白表達在葡萄胎的發(fā)生及惡變中的作用　中國醫(yī)學科學院學報25<4>, 朱長琨，葉大風，謝幸，程曉東，陳懷增，呂衛(wèi)國
　　27．卵巢癌細胞誘導T淋巴細胞凋亡的實驗研究　中華婦產(chǎn)科雜志38<9>, 汪輝，李曉，謝幸，呂衛(wèi)國，葉大風，陳懷增，程琪
　　28．幾種細胞因子對人臍血CD34+干細胞在體外誘導擴增為樹突狀細胞的研究　中華微生物學與免疫學雜志24<2>, 葉楓，謝幸，葉大風，陳懷增，呂衛(wèi)國
　　29．上皮性卵巢癌患者腹水白介素-10水平與其腹腔免疫功能缺陷關(guān)系的探討　癌癥23<5>, 周建維，程琪，謝幸，陳懷增，葉大風，呂衛(wèi)國
　　30．phosphorylation of signal transducer and activators of transcription 3 induced by vascular endothelial growth factor in ovarian carcinoma cell line in vitro生長因子體外刺激卵巢癌細胞株信號轉(zhuǎn)導及轉(zhuǎn)錄激活因子3　中華婦產(chǎn)科雜志39<6>, 王芬芬，陳懷增，謝幸，葉楓，葉大風，呂衛(wèi)國，丁志明
　　31．Effect Of Vascular Endothelial Growth Factor (VEGF) On Differentiation And Function Of Dendritic Cells Generated From CD34+ Hematopoietic Progenitor Cells In VitroVEGF對CD34+干/祖細胞來源的樹突狀細胞分化及功能的影響　中華血液學雜志25<9>, 葉楓，陳懷增，謝幸，呂衛(wèi)國
　　32．白細胞介素-2受體基因轉(zhuǎn)染人外周血淋巴細胞的初步研究　中國學術(shù)期刊文摘5<2>, 謝幸，葉大風，陳懷增，呂衛(wèi)國，程蓓
　　33．白介素-2及其受體基因?qū)θ送庵苎馨图毎麣⒙殉舶┘毎饔玫挠绊憽≈袊鴮W術(shù)期刊文摘5<6>, 葉大風，謝幸，陳懷增，呂衛(wèi)國，程蓓
　　34．IL-2基因轉(zhuǎn)染對人卵巢癌細胞增殖、凋亡和MHC-Ⅱ的影響　浙江醫(yī)學23<2>, 葉大風; 謝幸; 陳懷增; 呂衛(wèi)國; 程蓓
　　35．超排卵時卵泡發(fā)育數(shù)與顆粒細胞胰島素樣生長因子Ⅰ受體的表達　中華婦產(chǎn)科雜志36<2>, 陳丹青，石一復，陳懷增
　　36．免疫重建荷人卵巢癌嚴重聯(lián)合免疫缺陷鼠腹腔移植模型的建立　中華醫(yī)學雜志82<9>, 朱華，葉大風，陳懷增，呂衛(wèi)國，謝幸
　　37．人免疫重建荷人HPV16陽性宮頸癌-SCID鼠模型的建立及其生物學特性研究　現(xiàn)代婦產(chǎn)科進展13<2>, 梁朝霞，程琪，陳懷增，謝幸，葉大風
　　38．Altered expression of cellular membrane molecules of HLA-DR, HLA-G and CD99 in cervical intraepithelial neoplasias and invasive squamous cell carcinoma．Altered expression of cellular membrane molecules of HLA-DR, HLA-G and CD99 in cervical intraepithel　78<22>, Zhou JH, Ye F, Chen HZ, Zhou CY, Lu WG, Xie X
　　39．Proportion of CD4+CD25+ regulatory T cell is increased in the patients with ovarian carcinomaProportion of CD4+CD25+ regulatory T cell is increased in the patients with ovarian carcinoma　23<5>, Li X, Ye DF, Xie X, Chen HZ, Lu WG
　　40．Ovarian carcinoma cells effectively inhibit differentiation and maturation of dendritic cells derived from hematopoietic progenitor cells in vitroOvarian carcinoma cells effectively inhibit differentiation and maturation of dendritic cells derive　Cancer Invest23<5>, Feng Ye, Huai-Zeng Chen,Xing Xie,Da-Feng Ye,Wei-Guo Lu,Zhi-Ming Ding
　　41．Tumor-infiltrating dendritic cells in epithelial ovarian carcinoma and correlation with the expression of vascular endothelial growth factor卵巢上皮性癌組織中腫瘤浸潤性樹突狀細胞的狀態(tài)及其與血管內(nèi)皮生長因子表達的相關(guān)性　中華婦產(chǎn)科雜志39<10>, 毛俞燕，陳懷增，謝幸，葉大風，呂衛(wèi)國
　　42．IL-2基因轉(zhuǎn)染的人卵巢癌細胞對人外周血淋巴細胞殺瘤功能的影響　實用婦產(chǎn)科雜志16<6>, 葉大風，呂衛(wèi)國，陳懷增，謝幸
　　43．人免疫重建荷人人乳頭瘤病毒16陽性宮頸癌-嚴重聯(lián)合免疫缺陷鼠模型的建立及其免疫學特性研究　中華醫(yī)學雜志84<17>, 梁朝霞，程琪，陳懷增，謝幸，葉大風
　　44．Effect of interleukin-7 gene transfection into ovarian carcinoma cell line SKOV3 in vitro and in vivoEffect of interleukin-7 gene transfection into ovarian carcinoma cell line SKOV3 in vitro and in viv　Gynecologic Oncology92<>, Xing Xie, Da-Feng Ye,Huai-Zeng Chen,Wei-Guo Lu,Yun-Feng Fu,Bei Cheng, Hua Zhu
　　45．Growth inhibition of interleukin-2 receptor gene-transduced peripheral blood lymphocytes on human ov　Chin Med J (Engl)114<3>, Dafeng Ye,Xing Xie,Weiguo Lu,Huaizeng Chen,Bei Cheng
　　46．人類生長抑素受體mRNA在原發(fā)性肝癌中的表達　中華消化雜志22<11>, 劉建生，彭淑牖，吳育蓮，陳懷增，彭承宏，Gao YY
　　47．人白細胞介素-7基因克隆及其真核表達載體的構(gòu)建　浙江大學學報（醫(yī)學版）31<3>, 程蓓，葉大風，謝幸，陳懷增，呂衛(wèi)國
　　48．卵巢癌細胞對T細胞信號轉(zhuǎn)導途徑JAK-STAT的影響　中華醫(yī)學雜志83<11>, 汪輝，謝幸，呂衛(wèi)國，葉大風，陳懷增，李曉，程琪
　　49．血管內(nèi)皮生長因子體外誘導CD34+造血干/祖細胞信號傳導與轉(zhuǎn)錄活化因子的活化　中國醫(yī)學科學院學報26<1>, 葉楓，葉大風，謝 幸，陳懷增，呂衛(wèi)國
　　50．Vascular endothelial growth factor (VEGF) and ovarian carcinoma cell supernatant activate signal transducers and activators of transcription (STATs) via VEGF receptor-2 (KDR) in human hemopoietic progVascular endothelial growth factor (VEGF) and ovarian carcinoma cell supernatant activate signal tra　Gynecologic Oncology94<>, Feng Ye, Huai-Zeng Chen,Xing Xie,Da-Feng Ye,Wei-Guo Lu,Zhi-Ming Ding
　　51．Tapasin和HLAⅠ類分子在人卵巢癌中的表達及相關(guān)性　中國腫瘤14<4>, 52．HPV16E7肽疫苗對人免疫重建荷人宮頸癌細胞株SiHa細胞SCID鼠免疫功能的影響　現(xiàn)代婦產(chǎn)科進展14<5>, 53．人乳頭瘤病毒的分子生物學特性研究現(xiàn)狀　國外醫(yī)學．微生物學分冊28<4>, 54．卵巢上皮癌細胞中VEGF和VEGFRs的表達與STATs的活化　中華腫瘤雜志27<1>, 55．卵巢癌組織中腫瘤浸潤淋巴細胞分布特征的研究　中國實用婦科與產(chǎn)科雜志21<7>, 56．宮頸癌遺傳易感性的研究進展　國外醫(yī)學，遺傳學分冊28<6>, 57．子宮頸鱗癌Ⅰb～Ⅱa期患者預后預測系統(tǒng)的建立及其臨床意義　中華婦產(chǎn)科雜志40<4>, 58．早期宮頸鱗癌患者微淋巴管的分布及其臨床意義　中華醫(yī)學雜志85<22>, 59．在全子宮切除術(shù)后標本中發(fā)現(xiàn)的浸潤性宮頸癌30例臨床分析　現(xiàn)代婦產(chǎn)科進展14<3>, 60．細胞分裂方式及其發(fā)生機制研究進展　醫(yī)學分子生物學雜志2<6>, 61．Loss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous carcinomaLoss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous c　European Journal of Gynacological Oncology28<6>, Chen H,Ye F, Zhang J, Lu W,Cheng Q, Xie X
　　62．Loss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous carcinomaLoss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous c　European Journal of Gynacological Oncology28<6>, Chen H,Ye F, Zhang J, Lu W,Cheng Q, Xie X
　　63．Loss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous carcinomaLoss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous c　European Journal of Gynacological Oncology28<6>, Chen H,Ye F, Zhang J, Lu W,Cheng Q, Xie X
　　64．Loss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous carcinomaLoss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous c　European Journal of Gynacological Oncology28<6>, Chen H,Ye F, Zhang J, Lu W,Cheng Q, Xie X
　　65．Loss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous carcinomaLoss of OPCML expression and the correlation with CpG island methylation and LOH in ovarian serous c　European Journal of Gynacological Oncology28<6>, Chen H,Ye F, Zhang J, Lu W,Cheng Q, Xie X
　　66．No association of the POLI Thr706Ala polymorphism with the risk of cervical carcinomaNo association of the POLI Thr706Ala polymorphism with the risk of cervical carcinoma　European Journal of Gynacological Oncology<>, Zhang J, Ye F, Cheng Q,Shen J, Chen H
　　67．Establishment of a cervical cancer model via inoculating SiHa Cells into humanized severe combined immunodeficient mice　《EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY》27<6>, 2006-08-25 　　
　　68．Fas-mediated pathway and apoptosis in normal cervix, cervical intraepithelial neoplasia and cervical squamous cancer　《ONCOLOGY REPORTS》16<2>, 2006-08-25
　　69．VEGF induces phosphorylation of STAT3 through binding VEGFR2 in ovarian carcinoma cells in vitro． Eur J Gynaecol Oncol　《EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY》27<6>, 2006-06-26 　　
　　70．基因組CpG島甲基化檢測技術(shù)研究進展　《國際遺傳學雜志（原：國外醫(yī)學：遺傳學分冊）》29<3>, 2006-06-15
　　71．11q22-q25區(qū)候選抑癌基因OPCML、POU2F3、CUL-5啟動子CpG島甲基化與子宮頸癌的發(fā)生　《實用腫瘤雜志》21<5>, 2006-05-25
　　72．漢族婦女中p21codon31單核苷酸多態(tài)性與宮頸癌易感性關(guān)系的研究　《現(xiàn)代婦產(chǎn)科進展》15<4>, 2006-04-25
　　73．卵巢上皮性癌OPCML基因的表達缺失和啟動子甲基化　《中國醫(yī)學科學院學報》28<2>, 2006-04-25
　　74．漢族婦女中p21codon31單核苷酸多態(tài)性與宮頸癌易感性關(guān)系的研究　《現(xiàn)代婦產(chǎn)科進展》15<4>, 2006-04-25
　　75．卵巢上皮性癌細胞培養(yǎng)上清液增強CD4^CD25^＋調(diào)節(jié)性T淋巴細胞增殖及免疫抑制功能的實驗研究　《中華婦產(chǎn)科雜志》41<3>, 2006-03-24
　　76．卵巢癌細胞培養(yǎng)上清誘導CD4^＋CD25^- T細胞分化為CD4^＋CD25^＋調(diào)節(jié)性T細胞　《中華微生物學和免疫學雜志》26<2>, 2006-02-24
　　77．局部晚期子宮頸癌新輔助化療價值的評估　《中華婦產(chǎn)科雜志》41<2>, 2006-02-24
　　78．陰道鏡直視下活檢診斷宮頸上皮內(nèi)瘤變準確性的評價　《中華醫(yī)學雜志》86<5>, 2006-02-07
　　79．人乳頭瘤病毒基因型檢測方法的研究進展　《國際檢驗醫(yī)學雜志（原：國外醫(yī)學：臨床生物化學與檢驗學分冊）》27<1>, 2006-01-25
　　80．宮頸癌及上皮內(nèi)瘤變?nèi)巳轭^瘤病毒基因型的檢測　《現(xiàn)代婦產(chǎn)科進展》15<1>, 2006-01-25
　　81．Altered expression of cellular membrane molecules of HLA-DR, HLA-G and CD99 in cervical intraepithelial neoplasias and invasive squamous cell carcinoma　《LIFE SCIENCES》78<22>, 2006-01-24 　　
　　82．Expression in Normal Early Placentas and Hydatidiform MolesExpression in Normal Early Placentas and Hydatidiform Moles　J Soc Gynecol Investig12<>, 20051201 Huaizeng Chen, Dafeng Ye, Xing Xie, Weiguo Lu, Changkun Zhu, Xiaodong Chen

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