四川大學(xué)生命科學(xué)學(xué)院導(dǎo)師：李娟 正文

　　李娟
　　
　　聯(lián)系電話：028-85415025；85412650；
　　電子郵件：lijuanhk@gmail.com

　　學(xué)習(xí)與工作經(jīng)歷
　　1990-1994：四川大學(xué)，理學(xué)學(xué)士
　　1994-1997：四川大學(xué)，理學(xué)碩士
　　1997-1999：成都生物制品研究所，實習(xí)研究員
　　1999-2003：香港大學(xué)動物學(xué)系，理學(xué)博士
　　2004-2006：香港大學(xué)動物學(xué)系, 博士后
　　2006-現(xiàn)在：四川大學(xué)生命科學(xué)院

　　研究內(nèi)容介紹
　　“下丘腦-垂體-靶器官”作用通路，是調(diào)節(jié)動物生長發(fā)育的主要途徑。李娟博士目前在國家自然科學(xué)基金, 國家高科技研究計劃（863），轉(zhuǎn)基因新品種培育專項支持下，以家雞為研究模型，關(guān)注“下丘腦-垂體-卵巢”通路，圍繞催乳素生成釋放機制，卵泡發(fā)育機制開展受體功能鑒定與基因網(wǎng)絡(luò)調(diào)控解析。

　　主要研究論文

　　1. Huang G, Li Juan*, Fu H, Yan Z, Bu G, He X, Wang Y. Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants. Domestic Animal Endocrinology (on line: DOI:10-1016/ j.domaniend. 2012.01.005), 2012 (* 通迅作者)
　　
　　2. Wang Y, Huang G, Li Juan, Meng F, He X. Leung F.C . Characterization of Chicken Secretin (SCT) and Secretin Receptor (SCTR) Genes: A Novel Secretin-like Peptide (SCT-LP) and Secretin Encoded in a Single Gene. Molecular and Cellular Endocrinology, 348: 270-280, 2012

　　3. Wang Y, Wang CY, Wu Y, Huang G, Li Juan, Leung F C. Identification of the Receptors for Prolactin-releasing Peptide (PrRP) and Carassius RFamide Peptide (C-RFa) in Chickens. Endocrinology 153, p1-14 (DOI: 10.1210/en.2011-1719), 2012

　　4. Wang Y, Li Juan, Kwok AHY, Ge W & Lueng FC. A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: Cloning and Characterization of its tissue expression. General and Comparative Endocrinology 166: 200-210, 2010

　　5. Wang Y, Li Juan, C. Wang CY, Kwok AHY, Zhang X & Leung FC. Characterization of the receptors for chicken GHRH and GHRH-related peptides: Identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP). Domestic Animal Endocrinology 38: 13-31, 2010

　　6. Wang J, Wang Y, Li X, Li Juan* and Leung FC. Cloning, tissue distribution and functional characterization of chicken glucagon receptor. Poultry Science 87：2678-2688, 2008 (*通訊作者)

　　7. Li Juan, Wang X, and Leung FC. The intragenomic polymorphism of a partially inverted repeat (PIR) in Gallus gallus domesticus, potential role of inverted repeats in satellite DNAs evolution. Gene 387:118-125, 2007

　　8. Wang Y, Li Juan, Wang CY, Kwok AH, and Leung FC. Epidermal growth factor receptor (EGFR) ligands in the chicken ovary: evidence for heparin-binding EGF-like growth factor (HB-EGF) as a potential oocyte-derived signal to control granulosa cell proliferation and HB-EGF and kit ligand expression. Endocrinology 148:3426-3440, 2007

　　9. Wang Y, Li Juan, Wang CY, Kwok AH, and Leung FC. Identification of the endogenous ligands for chicken growth hormone-releasing hormone (GHRH) receptor: evidence for a separate 　　　gene encoding GHRH in submammalian vertebrates. Endocrinology 148:2405-2416, 2007

　10. Wang Y, Wang Z, Li Juan, Wang Y and Leung FC. Database for chicken full-length cDNAs. Physiol Genomics 28:141-145, 2007

　　11. Li Juan and Leung FC. A CR1 element is embedded in a novel tandem repeat (HinfI repeat) within the chicken genome. Genome 49:97-103, 2006

　　12. Wang CY, Wang Y, Li Juan and Leung FC. Expression profiles of growth hormone-releasing hormone and growth hormone-releasing hormone receptor during chicken embryonic pituitary 　　development. Poultry Science 85:569-576, 2006

　　13. Guan Y, Peris JSM, Zheng B, Poon LLM, Chan KH, Zeng FY, Chan CWM, Chen JD, Chow KYC, Hon CC, Hui KH, Li Juan, Li VYY, Wang Y, Leung SW, Yuen KY, Leung FC. Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome. Lancet 263:99-104, 2004

　　14. Zeng FY, Chan CW., Chen JD, Chow KYC, Hon CC, Hui KH, Li Juan, Li VYY, Wang Y, Leung SW, Yuen KY, Leung FC. The complete genome sequence of severe acute respiratory syndrome coronavirus strain HKU-39849. Experimental Biology and Medicine 288:866-873, 2003

　　15. Wang X, Li Juan and Leung FC. Partially inverted tandem repeat isolated from pericentric region of chicken chromosome 8. Chromosome Res 10:73-82, 2002
　　
　　16. Li Juan, Wang X and Leung FC. Partially inverted repetitive satellite DNA: A potential indicator for genetic homozygosity in chicken. 7th World Congress on Genetics Applied to Livestock Production 33:113-115, 2002

　　獲獎
　　第七屆大學(xué)生《挑戰(zhàn)杯》課外學(xué)術(shù)活動競賽：代表香港大學(xué)獲特等獎
　　2008， 2011年度四川大學(xué)青年骨干教師獎
　　 

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