南京農(nóng)業(yè)大學植物保護學院導師：吳益東 正文

　　吳益東 老師個人簡介：
　　吳益東，教授，博士生導師。1994年獲得南京農(nóng)業(yè)大學昆蟲專業(yè)博士學位，2001年晉升教授。先后在英國Rothamsted研究所、法國CIRAD和澳大利亞墨爾本大學遺傳系進行2年合作研究。長期從事農(nóng)業(yè)害蟲抗藥性研究，主持和承擔國家自然科學基金、863、轉(zhuǎn)基因生物品種培育重大科研專項、行業(yè)科技專項等課題15項。曾獲教育部科技進步獎二等獎1項（1999，第1完成人）、教育部自然科學獎二等獎1項（2006，第2完成人）、國家科學技術(shù)進步獎二等獎1項（2010，第3完成人）。先后獲得教育部首屆高校青年教師獎（1999）、江蘇省第六屆青年科技獎（2000）、江蘇省"333高層次人才培養(yǎng)工程"首批中青年科技領(lǐng)軍人才（2007）、“新世紀百千萬人才工程”國家級人選（2009）。

　　研究方向：
　　昆蟲分子毒理，害蟲抗藥性，Bt作物抗性監(jiān)測與治理

　　聯(lián)系方式：
　　 Tel: 025-84395261, e-mail:

　　主持的主要科研項目：
　　 * 棉鈴蟲Cry1Ac抗性顯性遺傳品系的抗性機理及適合度，國家自然科學基金，2011-2013.
　　 * Bt毒素Cry1Ac與棉鈴蟲中腸受體鈣粘蛋白和氨肽酶的互作，國家自然科學基金，2009-2011.
　　 * 棉鈴蟲對Bt棉花抗性頻率監(jiān)測與風險管理,轉(zhuǎn)基因生物新品種培育重大專項，2011-2015.
　　 * 小菜蛾抗藥性監(jiān)測與機理，公益性行業(yè)科技項目，2011-2015.
　　 * 棉鈴蟲對Bt毒素抗性的高通量分子檢測技術(shù)，863項目，2007-2010.
　　 * 殺蟲藥劑誘導害蟲再猖獗的機制，973項目子課題骨干，2006-2010.
　　 * 棉鈴蟲田間種群鈣粘蛋白基因變異與對Bt毒素抗性的關(guān)系，國家自然科學基金，2006-2008.
　　 * 用RNA干涉技術(shù)研究棉鈴蟲細胞色素P450基因與抗藥性的關(guān)系，國家自然科學基金，2005-2007.
　　 * 小規(guī)模棉花生產(chǎn)體系棉鈴蟲的可持續(xù)控制，國際合作項目(CFC/ICAC/14)，2000-2005.
　　 * BT棉在中國的農(nóng)業(yè)和環(huán)境適合性評估，歐盟第五框架國際合作項目，2001-2005.
　　 * 棉鈴蟲細胞色素P450同工酶的純化及抗性基因檢測，國家自然科學基金項目，1998-2000.
　　 * 棉鈴蟲細胞色素P450與抗藥性的關(guān)系，國家自然科學基金項目，1995-1997.
　　
　　  
　　發(fā)表的主要論文 (*通訊作者)
　　Haonan Zhang, Wei Yin, Jing Zhao, Lin Jin, Yihua Yang, Shuwen Wu, Bruce E. Tabashnik, Yidong Wu*. 2011. Early Warning of Cotton Bollworm Resistance Associated with Intensive Planting of Bt Cotton in China. PLoS ONE 6(8): e22874.
　　Shuwen Wu, Yihua Yang, Guorui Yuan, Peter M. Campbell, Mark G. Teese, Robyn J. Russell, John G. Oakeshott and Yidong Wu*. 2011. Overexpressed esterases in a fenvalerate resistant strain of the cotton bollworm, Helicoverpa armigera. Insect Biochemistry and Molecular Biology 41(1):14-21.
　　Zhenyu Wang, Haifei Yan, Yihua Yang and Yidong Wu*. 2010. Biotype and insecticide resistance status of the whitefly Bemisia tabaci from China. Pest Management Science.66(12):1360-1366.
　　Guorui Yuan, Weiyue Gao, Yihua Yang, Yidong Wu*. 2010. Molecular cloning, genomic structure and genetic mapping of two Rdl-orthologous genes of GABA receptors in the diamondback moth, Plutella xylostella. Achives of Insect Biochemistry and Physiology.74(2):81-90.
　　Youjing Gong, Chongli Wang, Yihua Yang, Shuwen Wu, Yidong Wu*. 2010. Characterization of resistance to Bacillus thuringiensis toxin Cry1Ac in Plutella xylostella from China. Journal of Invertebrate Pathology. 104(2):90-96.
　　Xingliang Wang, Xiangyong Li, Aidong Shen, Yidong Wu*. 2010. Baseline susceptibility of the diamondback moth (Lepidoptera: Plutellidae) to chlorantraniliprole in China. Journal of Economic Entomology. 103(3):843-848.
　　Xin Pu, Yihua Yang, Shuwen Wu, Yidong Wu*. 2010. Characterization of abamectin resistance in a field-evolved multi-resistant population of Plutella xylostella. Pest Management Science. 66(4):371-378.
　　Jing Zhao, Lin Jin, Yihua Yang, Yidong Wu*. 2010. Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicoverpa armigera. Insect Biochemistry and Molecular Biology. 40(2):113-118.
　　Cun-Zheng Zhang, Zhi-Yong Zhang, Xian-Jin Liu, Wayne Jiang, Yi-Dong Wu*. 2010. Dissipation and environmental fate of herbicide H-9201 in carrot plantings under field conditions. Food Chemistry. 119:874-879.
　　Zhenyu Wang, Mingde Yao, Yidong Wu*. 2009. Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B biotype Bemisia tabaci. Pest Management Science. 65(11):1189-1194.
　　Yidong Wu*,Jean-Michel Vassal,Monica Royer,Isabelle Pieretti. 2009. A single linkage group confers dominant resistance to Bacillus thuringiensis δ-endotoxin Cry1Ac in Helicoverpa armigera. Journal of Applied Entomology.133(5):375-380.
　　Yihua Yang,Yajun Yang,Weiyue Gao,Jingjie Guo,Yanhong Wu,Yidong Wu*. 2009. Introgression of a disrupted cadherin gene enables susceptible Helicoverpa armigera to obtain resistance to Bacillus thuringiensis toxin Cry1Ac. Bulletin of Entomological Research.99(2):175-181.
　　Yihua Yang,Lina Yue,Song Chen,Yidong Wu*. 2008. Functional expression of Helicoverpa armigera CYP9A12 and CYP9A14 in Saccharomyces cerevisiae. Pesticide Biochemistry and Physiology.92(2):101-105.
　　Xinjun Xu and Yidong Wu*. 2008. Disruption of Ha_BtR alters binding of Bacillus thuringiensis δ-endotoxin Cry1Ac to midgut BBMVs of Helicoverpa armigera. Journal of Invertebrate Pathology. 97(1):27-32.
　　Yajun Yang, Haiyan Chen, Yidong Wu*, Yihua Yang, and Shuwen Wu. 2007. Mutated cadherin alleles from a field population of Helicoverpa armigera confer resistance to Bacillus thuringiensis toxin Cry1Ac. Applied and Environmental Microbiology.71(21):6939-6944.
　　Lihua Wang and Yidong Wu*. 2007. Cross-resistance and biochemical mechanisms of abamectin resistance in the B-type Bemisia tabaci. Journal of Applied Entomology. 131(2):98-103.
　　Yihua Yang, Song Chen, Shuwen Wu, Lina Yue, Yidong Wu*. 2006. Constitutive overexpression of multiple cytochrome P450 genes associated with pyrethroid resistance in Helicoverpa armigera. Journal of Economic Entomology. 99(5):1784-1789.
　　Yajun Yang, Haiyan Chen, Shuwen Wu, Yihua Yang, Xinjun Xu, Yidong Wu*. 2006. Identification and molecular detection of a deletion mutation responsible for a truncated cadherin of Helicoverpa armigera. Insect Biochemistry and Molecular Biology.36(9):735-740.
　　Ageng Li, Yihua Yang, Shuwen Wu, Chao Li, Yidong Wu*. 2006. Investigation of resistance mechanisms to fipronil in the diamondback moth (Lepidoptera: Yponomeutidae). Journal of Economic Entomology. 99(3):914-919.
　　Xinjun Xu, Liangying Yu, Yidong Wu*. 2005. Disruption of a cadherin gene associated with resistance to Cry1Ac δ-endotoxin of Bacillus thuringiensis in Helicoverpa armigera. Applied and Environmental Microbiology. 71(2):948-954.
　　Song Chen, Yihua Yang, Yidong Wu*. 2005. Correlation between fenvalerate resistance and cytochrome P450 mediated O-demethylation activity in Helicoverpa armigera (Lepidoptera: Noctuidae). Journal of Economic Entomology. 98(3):943-946.
　　Yang E., Yang Y., Wu S., Wu Y.*. 2005. Relative contribution of detoxifying enzymes to pyrethroid resistance in a resistant strain of Helicoverpa armigera. Journal of Applied Entomology. 129(9):521-525.
　　Yang Y., Wu Y.*, Chen S., Devine G.J., Denholm I., Jewess P., Moores G.D. 2004. The involvement of microsomal oxidases in pyrethroid resistance in Helicoverpa armigera from Asia. Insect Biochemistry and Molecular Biology. 34(8):763-773.

 

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